Launched in 2005, the Empowering Africa’s Young People Initiative (EAYPI) helped prevent the spread of HIV among youth in Sub-Saharan Africa through scaling up programs proven to promote healthy behaviors. The five-year initiative, supported through the President’s Emergency Plan for AIDS Relief (PEPFAR), and administered by USAID, reached young people, ages 10 to 25, in three African countries. Through EAYPI, IYF provided support to 13 local youth-serving organizations to implement activities and provide technical assistance through on-site mentoring of technical personnel, workshops, seminars, as well as curricula and technical guidelines.